- A Better English Setter Rescue
Based in NJ, with members throughout the US: English Setters
- Alabama Boston Terrier Rescue, Inc.
Courtland, Alabama: Boston Terriers
- American Brittany Rescue
- American Bullmastiff Association Rescue Service
- American Miniature Schnauzer Rescue
Nationwide: Miniature Schnauzers
- American Pointer Rescue, Inc.
Nationwide and Canada: English Pointers
- Arabian Rescue Mission, Inc.
Based in Wantage, New Jersey: Horses
- Arkabutla Rescue Rehabilitation & Foster – ARRF
Coldwater, Mississippi: Dogs (including aggressive and behavioral issue dogs), and livestock (horses, donkeys, pigs)
- Bark And Roll Rescue Companions
Baton Rouge, LA: Small Breed Dogs & Puppies
- Bee is for Bully, Inc.
Clinton, Mississippi: English, French, American, and Olde English Bulldogs
- Cavalier Rescue USA
Nationwide: Cavalier King Charles Spaniels
- Col. Potter Cairn Rescue Network
Nationwide: Cairn Terriers
- Dixie Adoptables at Lucedale Animal Shelter
Lucedale, MS: Dogs and Cats
- Eskie Rescuers United
Based in Maryland, with volunteers throughout the Eastern United States: American Eskimo Dogs
- Fancy Feline Rescue of the South, Inc.
Powder Springs, GA: Cats – purebred and high mixes
- Friends of Rescued Mastiffs, Inc.
United States: English Mastiffs
- Full Moon Farm Wolfdog Sanctuary
Western North Carolina: Wolfdogs
- GetALong Dachshund Rescue
National Rescue: Dachshunds
- Grassroots Animal Rescue of MS
Starkville, MS: Dogs, Puppies
- Great Babies Rescue, Inc.
Paoli, Indiana: Primarily a Great Dane rescue, specializing in special needs and last chance dogs
- Greyhound Pets of America La. & Ms.
Covington, Louisiana: Greyhounds retired from racing tracks
- GypsySoul Rottweiler Rescue
Pittsburg, KS: Primarily Rottweilers, but will take dogs of all breeds and backgrounds
- Homeward Horse and Hound
Hattiesburg, MS: Hunting (Hound) Breeds, Horses
- Italian Greyhound Rescue Foundation
Nationwide: Italian Greyhounds
- Just Giants Rescue
Midwest: Giant breed dogs
- Lifeline Dog Rescue
Inverness, FL: Weimaraners and other breeds of dogs
- Magic Happens Rabbit Rescue
Baton Rouge, LA: Rabbits, guinea pigs
- Memphis Rottweiler Rescue
Memphis, TN: Rottweilers, Pit Bulls & other Bully Breeds
- MidSouth Pug Rescue Inc
Memphis, TN: Pugs
- Natchez-Adams County Humane Society
Natchez, MS: Dogs, Cats
- No Borders Bulldog Rescue
Based in Dallas, TX: Bulldogs (American, English, French, Olde English)
- Northwest Arkansas Rescue of Canines
Harrison, AR: Dogs
- Our English Setter Rescue
Nationwide: English Setters
- Papillon Haven Rescue
- Pet Assistance, Inc.
New Preston, Connecticut: We subsidize urgent and emergency veterinary care for pets of people in financial need.
- Pointer Rescue, Org
North America: English Pointer Dogs
- Rescue Revolution of Mississippi
Jackson, Mississippi Area: Dogs, Spay & Neuter
- Rescue Tails
Brookhaven, MS: Dogs, Cats
- Rocky Mountain Siamese Rescue
Greeley, Colorado: Siamese cats and other Oriental breeds
- S’Wheat Rescues & Adoptions, Inc.
Nationwide: Soft Coated Wheaten Terriers, Wheatables
- Save One Soul Animal Rescue League
Based in Rhode Island, serving Southern New England: Dogs from the Southern U.S.
- Save Rocky the Great Dane Rescue and Rehab aka SRGDRR Inc
Based in Texas, SRGDRR supports Danes in need from coast to coast: Great Danes, Great Dane mixes
- Shaw Pit Bull Rescue, Inc.
Columbus, Mississippi: Pit Bulls
- Southern Friends Animal Society
Southaven, MS: Dogs, Cats, Spay & Neuter
- Southern States Rescued Rottweilers
White Hall, AR: Rottweilers and Rottweiler mixes
- Starting Over Airedale Rescue
Howell, Michigan: Airedale Terriers
- STOLA – Saluki Tree of Life Alliance
Based in California; operates throughout the continental U.S.: Saluki hounds
- Tired Dog Rescue
- Underdog Animal Society
Gulfport, MS: Dogs, Cats
- Weimaraner Rescue of the South
MS, AL and parts of LA, TN and GA: Weimaraners